R & S Drug #1

821 W Main St
Duncan, OK 73533
Due to COVID-19 requirements and recommendations, many Oklahoma businesses and attractions have made changes to their hours of operation and available services. We encourage all potential visitors to contact the business or attraction directly before visiting for up-to-date information. For Oklahoma State Health Department information and recommendations, visit the COVID-19 resource page.

R & S Drug #1

821 W Main St
Duncan, OK 73533

A pharmacy, soda fountain and cafe all in one nostalgic location, R & S Drug #1 in Duncan is known for its old-fashioned atmosphere reminiscent of a bygone American era. Open since 1945, R & S offers everything from freshly-baked pies and confections to a gift shop featuring local goods. Stop in for lunch and sip on the soup of the day and chow down on a veggie wrap before polishing the meal off with an ice cream sundae or cherry limeade. Be sure to shop the aisles for jewelry, sports team apparel, home decor and much more.




Monday: 9:00 am - 6:00 pm
Tuesday: 9:00 am - 6:00 pm
Wednesday: 9:00 am - 6:00 pm
Thursday: 9:00 am - 6:00 pm
Friday: 9:00 am - 6:00 pm
Saturday: 9:00 am - 4:00 pm
A special thanks to our advertisers